For our applications opening the gap is a VERY bad idea. You will blow out the spark if your gap is too big, or if you run more boost. We use the Iridium plugs (not platnium) in everything we build and usaully gap them from .020 to .028 depending on the application. We will run a NGK heat range 6 or 7 in most everything (TR6ix or TR7ix for vortecs or UR6ix / UR7ix for stock heads)
Do this with stock or MSD ignition. The MSD will not kill your plugs any faster than you'll ever notice , unless you run a pro mag 44..................thats another story.